Photo by nevin xavier

Hotels in Santa Cruz

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Where to stay in Santa Cruz?

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Top landmarks in Santa Cruz

Learn more about Santa Cruz

Santa Cruz is well-known for its attractions such as Huascaren National Park and Punta Union.

Team posing for the epic shot in Punta union pass in the Peruvian Andes
Photo by nevin xavier
Open Photo by nevin xavier
A tranquil hotel pool encircled by beautiful arches, enhancing the ambiance for leisure and relaxation.

Summer Getaway Sale

Save 25% or more on select hotels, and earn 50% more rewards on all properties. Book by May 26 and travel by Sep 30, 2025. See terms*

Frequently asked questions

What accommodations do travelers like in Santa Cruz?
Can I book a refundable hotel in Santa Cruz?
If you want the flexibility to change your plans to Santa Cruz, most properties provide refundable* bookable rates. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow down the results.
Where can I stay if I'm visiting Santa Cruz for a family-friendly trip?
Parents traveling with children may want to consider Santa Cruz Lodge - Casa Andina Partner Hotel.
What will the weather in Santa Cruz be like during my visit?
The warmest months in Santa Cruz are usually August and July with an average temp of 53°F. July and August are the chilliest months when the average temp is 53°F. The rainiest months are March and January.
Why should I book my Santa Cruz hotel through Hotels.com?
There are plenty of reasons to book your Santa Cruz travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Terms and conditions

*Book by 5/26/2025 11:59 pm in hotel property local time. Stay between 4/17/2025-9/30/2025. Member Prices are available to Hotels.com® app users and One Key members. Limited availability, blackout periods may apply.

OneKeyCash is not redeemable for cash and can only be used on Hotels.com®, Expedia®, and Vrbo®.

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