Hotels in Santo Antonio

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Apr 27 - Apr 28
Tomorrow
Apr 28 - Apr 29
Next weekend
May 2 - May 4
In two weeks
May 9 - May 11

Where to stay in Santo Antonio?

Locke de Santa Joana
Seasonal outdoor pool, pool umbrellas, sun loungers

Locke de Santa Joana

4.0 star property
9.6 out of 10, Exceptional, (774)
The price is $148
includes taxes & fees
$131 per night
Apr 30 - May 1
Locke de Santa Joana
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Great weekend hotel deals in Santo Antonio

Showing deals for:May 9 - May 11

Image gallery for EPIC SANA Marques Hotel

Indoor pool, outdoor pool, pool umbrellas, sun loungers
VIP Access

EPIC SANA Marques Hotel

5.0 star property
Lisbon
9.8/10Exceptional (1,005 reviews)
30% off
Price is $261
per night
$572 total
includes taxes & fees
EPIC SANA Marques Hotel

Top landmarks in Santo Antonio

Rossio Square showing a fountain, street scenes and heritage elements

Rossio Square

Rossio Square is worth passing through for a few pics when in Baixa. Our travelers also like this historical area for its riverfront setting. Santa Maria Maior has other landmarks you might want to visit such as Belém Tower.

See properties in Rossio Square
Rossio Square

Learn more about Santo Antonio

Santo Antonio is well-known for its gardens while top attractions include Avenida da Liberdade. This welcoming city has something for everyone including sights like Marquis of Pombal Square and Medeiros e Almeida Museum within a lively setting.

See all hotels in Santo Antonio
Santo Antonio which includes a river or creek, outdoor eating and street scenes
A tranquil hotel pool encircled by beautiful arches, enhancing the ambiance for leisure and relaxation.

Summer Getaway Sale

Save 25% or more on select hotels, and earn 50% more rewards on all properties. Book by May 26 and travel by Sep 30, 2025. See terms*
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Frequently asked questions

What accommodations do travelers like in Santo Antonio?
Hotel das Amoreiras - Small Luxury Hotels of the World, Hotel Britania Art Deco, a Lisbon Heritage Collection and Valverde Lisboa Hotel & Garden - Relais & Châteaux are all properties that our guests really like.
Where can I get free parking with my stay in Santo Antonio?
Park your car for free at Hotel Florida.
Can I book a refundable accommodation in Santo Antonio?
If you want the flexibility to change your plans to Santo Antonio, most hotels provide refundable* rates you can book. You can find these accommodations by searching our site and using the “fully refundable” filter to narrow down the results.
Where can I stay with my pet in Santo Antonio?
Your animal companion is welcome at these pet-friendly hotels: Hotel Lisboa Plaza, a Lisbon Heritage Collection, Sofitel Lisbon Liberdade, and CASA AMORA Studio Apartments.
Which Santo Antonio hotels do our guests like for their central location?
Our guests rave about the location of these properties: easyHotel Lisbon and EPIC SANA Marques Hotel.
Where can I stay in Santo Antonio if I'm looking for a budget-friendly accommodation?
EasyHotel Lisbon is an accommodation you might want to consider that’ll save you money. You can browse all 14 choices on our site.
Where can I stay in Santo Antonio if I want a vacation home instead of a hotel?
If you’re looking for a good alternative to a hotel, look over our selection of 49 vacation homes. In addition, you can choose from 543 apartments.
Where can I stay if I'm visiting Santo Antonio with my family?
Parents traveling with children may want to consider EPIC SANA Lisboa Hotel, Sofitel Lisbon Liberdade and Turim Restauradores Hotel. You can also review 5 options available on our site.
Where should I stay in Santo Antonio for a vacation with my partner?
Casa Oliver Príncipe Real and Memmo Príncipe Real are great options for a romantic getaway.
Where should I stay in Santo Antonio if I want a luxury hotel?
Experience luxury when you stay at EPIC SANA Lisboa Hotel, Sofitel Lisbon Liberdade and Memmo Principe Real, Lisbon, a Member of Design Hotels.
What will the weather in Santo Antonio be like during my trip?
The warmest months in Santo Antonio are usually August and July with an average temp of 70°F. February and January are the chilliest months when the average temp is 55°F. The rainiest months are November and December.
Why should I book my Santo Antonio accommodation with Hotels.com?
There are plenty of reasons to book your Santo Antonio travel with us: our free cancellations on selected hotels* gives you the flexibility you’re looking for, and with One Key™, our rewards program, you will be able to earn and use OneKeyCash™** on all eligible bookings such as hotels, car rentals, flights, vacation rentals and more on Hotels.com, Expedia and Vrbo.

Terms and conditions

*Book by 5/26/2025 11:59 pm in hotel property local time. Stay between 4/17/2025-9/30/2025. Member Prices are available to Hotels.com® app users and One Key members. Limited availability, blackout periods may apply.

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